Chelation Therapy for Treatment of Heart Disease

Usually thought of as an alternative remedy for heavy metal toxicity, chelation therapy is now being studied for treatment of heart disease.

November 6, 2012
chelation therapy treatment of heart diseaseSource: Getty Images

Chelation therapy is a usually used for heavy metal toxicity, but it may also be an option for the treatment of heart disease.

I think of chelation therapy as sort of fringe-y, so I was surprised to hear today that the National Institutes of Health has studied it as a possible treatment for heart disease. Chelation generally involves receiving intravenous infusions of compounds that bind with harmful substances like heavy metals to help remove them from your body, and some have speculated that chelation can remove the fatty deposits that line the arteries of people with atherosclerosis.

Researchers did a double-blind, placebo-controlled trial to see if there's any truth to the idea that chelation therapy can help the heart. More than 1700 people who'd previously had heart attacks received 40 IV infusions containing either the chelating agent disodium EDTA or a placebo.  The results of the study were . . . inconclusive. The study subjects receiving chelation were slightly less likely to experience cardiovascular events (heart attacks, stroke, etc) than the control group (26% vs 30%). However, that's a tiny difference, and as the New York Times explains, it's possible that the control group did worse because the placebo they received contained small amounts of sugar that may have negatively impacted their blood sugar, or that the chelation group did better because of vitamin C and blood thinners that were also administered through their IVs, and not because of the chelating agents.

So if you've suffered a heart attack or have been diagnosed with atherosclerosis, this isn't news you can use: don't go searching for a chelation therapist at this point. This is how the lead study author, Gervasio A. Lamas, M.D., chief of Columbia University Division of Cardiology at Mount Sinai Medical Center in Miami Beach, cautiously summed up the results of the research in a statement:

We have to look carefully at these unexpected results. Although not approved by the Food and Drug Administration for treating heart disease, chelation therapy has been used for over 50 years and has generally been believed by conventional medical practitioners and cardiologists to be without value. A definitive answer on chelation therapy will take much additional research. The most exciting part of this study is that there may be an unexpected signal of benefit. We need to understand whether the signal is true, or whether it occurred by chance."

More about the prevention and treatment of heart disease:

4 Supplements to Halt Heart Disease

Could Your Multivitamin Cause Atherosclerosis?

Heart Attacks: Two Weird Risk Factors

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Anonymous | Nov 7, 2012
If these results were the other way around the big pharma companies would be screaming that chelation resulted in 14% more incidents and deaths. Instead they talk about the 4% difference being insignificant. However look at it this way 26% with incidents vs. 30% with incidents is not just a 4% difference. It means that those getting chelation had a 14% better chance of not having an incident (26% divided by 30% - 1). They should list chelation as a potential avenue of treatment so insurance companies will pay for it and then monitor a much larger section of the public and see what the real benefits are.
Celeste Perron | Nov 7, 2012

Very good points, thanks for your comment!

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